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Neurotoxic effects of methylene chloride : are they long lasting in humans?

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<title>Neurotoxic effects of methylene chloride</title>
<subTitle>: are they long lasting in humans?</subTitle>
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<title>British journal of industrial medicine</title>
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<name type="personal" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080138233">
<namePart>Lash, Andrea A.</namePart>
<nameIdentifier>MAPA20080138233</nameIdentifier>
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<dateIssued encoding="marc">1991</dateIssued>
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<abstract displayLabel="Summary">This study was designed to test the hypothesis that long term exposure to comparatively low concentrations of methylene chloride (MC) produces lasting effects on the central nervous system (CNS). The design of the study differs from that of most retrospective studies of solvent exposures because the study groups were constructed specifically to meet particular design goals. The aim of this study was to eliminate current exposures to MC so that chronic effects could be studied, to maximise the exposure contrast and thus the posibility of observing effects, to control for potential confounding variables, and to examine sources of selection bias that could limit the generalisation of the research findings</abstract>
<note type="statement of responsibility">Andrea A. Lash... [et al.]</note>
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<topic>Epidemiología</topic>
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<topic>Neurología</topic>
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<topic>Sistema Nervioso Central</topic>
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<topic>Disolventes industriales</topic>
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<topic>Cloruro de metileno</topic>
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<topic>Toxicidad</topic>
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<title>British journal of industrial medicine</title>
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<publisher>London and Margate</publisher>
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<part>
<text>nº 6, June 1991 ; p. 418-426</text>
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