A Simulation study of physiological factors affecting pharmacokinetic behaviour of organic solvent

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      <subfield code="a">A Simulation study of physiological factors affecting pharmacokinetic behaviour of organic solvent</subfield>
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      <subfield code="a">This paper discusses how physiological factors may influence the pharmacokinetic behaviour of inhaled organic solvent vapours, especially in relation to monitoring of biological exposure. To illustrate the discussion a computer based physiological pharmacokinetic model was used describing quantitatively the influence of body size, body fat content, and sex on the pharmacokienetic behaviour of trichloroethylene. Body build (body weight and body fat content), also affected the pharmacokinetic behaviour of this solvent</subfield>
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      <subfield code="a">British journal of industrial medicine</subfield>
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      <subfield code="t">British journal of industrial medicine</subfield>
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      <subfield code="g">nº 5, May 1991 ; p. 342-347</subfield>
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