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Ethanol and food deprivation induced enhancement of hepatotoxicity in rats given carbon tetrachloride at low concentration
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MAP20071016984
Ikatsu, H. ‌
Ethanol and food deprivation induced enhancement of hepatotoxicity in rats given carbon tetrachloride at low concentration / H. Ikatsu, T. Okino, T. Nakajima
Sumario: It is difficult to extrapolate the dose-response relation in CCl4 (carbon tetrachloride) induced hepatotoxicity from the high concentrations used in animal studies to the low concentrations generally encountered by man in the workplace. Therefore, the dose-response relation of inhalation exposure at low concentration must be investigated when trying to determine a TLV of exposure concentration for man. In the present study, it is investigated the dose-response relations of CCl4 induced hepatic damage in chronic ethanol treated and one day food deprived rats with biochemical and histopathological methods
En: British journal of industrial medicine. - London and Margate. - nº 9, September 1991 ; p. 636-642
1. Higiene industrial ‌. 2. Contaminantes químicos ‌. 3. Tetracloruro de carbono ‌. 4. Disolventes industriales ‌. 5. Valores TLV ‌. 6. Medicina laboral ‌. 7. Experimentos ‌. 8. Etanol ‌. I. Okino, T. ‌. II. Nakajima, Tamie ‌. III. Title. IV. Título: British journal of industrial medicine.