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What makes silica toxic?

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MARC record
Tag12Value
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001  MAP20071017048
003  MAP
005  20080418114908.0
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008  940128e19920301gbr|||| | |00010|eng d
035  ‎$a‎6800002972
040  ‎$a‎MAP‎$b‎spa
084  ‎$a‎873
1001 ‎$0‎MAPA20080008697‎$a‎Bagchi, N.
24510‎$a‎What makes silica toxic?‎$c‎N. Bagchi
520  ‎$a‎Published data suggest that particle charge could be related to its toxicity. Respirable particles containing silica were therefore collected in foundries and their charge measured. These particles carried high levels of positive charge that were related to low humidity. incubating these particles with pulmonary macrophages from mice produced detectable activities of collagenase, aprecursor of silicosis. These experiments confirm that the toxicity of silica particles is likely to be because of the positive charge they carry
65011‎$0‎MAPA20080576615‎$a‎Medicina laboral
65011‎$0‎MAPA20080619480‎$a‎Enfermedades profesionales
65011‎$0‎MAPA20080552671‎$a‎Silicosis
65011‎$0‎MAPA20080542313‎$a‎Sílice
65011‎$0‎MAPA20080573348‎$a‎Polvo de sílice
65011‎$0‎MAPA20080562410‎$a‎Experimentos
65011‎$0‎MAPA20080552824‎$a‎Toxicidad
7400 ‎$a‎British journal of industrial medicine
7730 ‎$t‎British journal of industrial medicine‎$d‎London and Margate‎$g‎nº 3, March 1992 ; p. 163-166