Variations of some parameters of enzyme induction in chemical workers

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<title>Variations of some parameters of enzyme induction in chemical workers</title>
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<title>The Annals of occupational hygiene</title>
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<namePart>Dolara, P.</namePart>
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<dateIssued encoding="marc">1982</dateIssued>
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<abstract displayLabel="Summary">Several parameters related to mono-oxygenase activity were followed in a population of chemical workers and controls. Workers exposed to toluene and xylene had a significant increase of urinary glucaric acid, that was correlated with hippuric acid excretion. On the other hand, workers exposed to pigments showed a marked increase of antipyrine half-life. A dose-related decrease of liver N-demethylase was induced in rats by the administration of a mixture of three of the pigments in use in the plant. The exposure to different chemicals in the workplace seemed to induce a complicated variation of mono-oxygenase levels, some enzyme being inhibited and others induced in the same group of workers</abstract>
<note type="statement of responsibility">P. Dolara... [et al.]</note>
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<text>nº 1, 1982 ; p. 27-32</text>
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