Airborne endotoxin associated with industrial-scale production of protein products in gram-negative bacteria
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| Tag | 1 | 2 | Value |
|---|---|---|---|
| LDR | 00000nab a2200000 i 4500 | ||
| 001 | MAP20071020017 | ||
| 003 | MAP | ||
| 005 | 20080418120043.0 | ||
| 007 | hzruuu---uuuu | ||
| 008 | 940623e19880801usa|||| | |00010|eng d | ||
| 035 | $a6800013444 | ||
| 040 | $aMAP$bspa | ||
| 084 | $a872 | ||
| 245 | 1 | 0 | $aAirborne endotoxin associated with industrial-scale production of protein products in gram-negative bacteria$cRussell B. Palchak... [et al.] |
| 520 | $aHuman and animal proteins of therapeutic value can be produced in E. coli, a gram-negative bacteria. Endotoxin, a cellular component, is reported to have clinically significant health effects. Operations had associated endotoxin levels ranging from 0.07 ng/m3 to 12.8 ng/m3. Utilizing a 10-fold safety factor under the threshold where clinically significant changes can be detected, an action level of 30 mg/m3 for large scale operations involving the use of E. coli was established. Operations conducted without engineering controls had maximum airborne endotoxin levels of 1812 ng/m3 | ||
| 650 | 1 | 1 | $0MAPA20080585679$aHigiene industrial |
| 650 | 1 | 1 | $0MAPA20080605278$aContaminantes químicos |
| 650 | 1 | 1 | $0MAPA20080613617$aContaminantes biológicos |
| 650 | 1 | 1 | $0MAPA20080558116$aEndotoxinas |
| 650 | 1 | 1 | $0MAPA20080588946$aAmbiente de trabajo |
| 650 | 1 | 1 | $0MAPA20080549855$aBacterias |
| 650 | 1 | 1 | $0MAPA20080570484$aRiesgo laboral |
| 700 | 1 | $0MAPA20080251215$aPalchak, Russell B. | |
| 740 | 0 | $aAmerican Industrial Hygiene Association journal | |
| 773 | 0 | $tAmerican Industrial Hygiene Association journal$dAkron, Ohio$gVol. 49, nº 8, August 1988 ; p. 420-421 |