Centro de Documentacion de Fundación MAPFRE - Airborne endotoxin associated with industrial-scale production of protein products in gram-negative bacteria

Notes: Sumario: Human and animal proteins of therapeutic value can be produced in E. coli, a gram-negative bacteria. Endotoxin, a cellular component, is reported to have clinically significant health effects. Operations had associated endotoxin levels ranging from 0.07 ng/m3 to 12.8 ng/m3. Utilizing a 10-fold safety factor under the threshold where clinically significant changes can be detected, an action level of 30 mg/m3 for large scale operations involving the use of E. coli was established. Operations conducted without engineering controls had maximum airborne endotoxin levels of 1812 ng/m3Related records: En: American Industrial Hygiene Association journal. - Akron, Ohio. - Vol. 49, nº 8, August 1988 ; p. 420-421Materia / lugar / evento: Higiene industrial Contaminantes químicos Contaminantes biológicos Endotoxinas Ambiente de trabajo Bacterias Riesgo laboral Otros autores: Palchak, Russell B.
Secondary titles: Título: American Industrial Hygiene Association journal
Other categories: 872