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MAP20071020740Some effects of jet-lag and their alleviation by melatonin / J. Arendt... [et al.]Sumario: Seventeen healthy volunteers were flown from London to San Francisco and remained there for 14 days prior to flight home. Subjects took melatonin or placebo in a double-blind design, at 18.00h local time for three days before the return flight and at bedtime in Great Britain for four days. These data suggest that MT can alleviate jet-lag after Eastward flight over eight time zones. Presumably its affects are primarily on sleep latency, quality, and directly or indirectly on some hormonal rhythmsEn: Ergonomics. - London [etc.]. - Vol. 30, nº 9, September 1987 ; p. 1379-13931. Ergonomía. 2. Aviones. 3. Biorritmos. 4. Ritmo circadiano. 5. Neurobiología. 6. Metabolitos. 7. Análisis estadístico. I. Arendt, J.. II. Title. III. Título: Ergonomics.