Acute and subchronic neurotoxicity studies with tri-n-butyl phosphate in adult sprague-dawley rats

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<title>Acute and subchronic neurotoxicity studies with tri-n-butyl phosphate in adult sprague-dawley rats</title>
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<title>American Industrial Hygiene Association journal</title>
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<name type="personal" usage="primary" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080025915">
<namePart>Healy, C.E.</namePart>
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<name type="personal" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080091538">
<namePart>Beyrouty, P.C.</namePart>
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<name type="personal" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080038793">
<namePart>Broxup, B.R.</namePart>
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<abstract displayLabel="Summary">Tri-n-butyl phosphate (TBP) is a liquid phosphate ester used as a component in the production of airline hydraulic fluids. The material previously had been found not to produce delayed neurotoxicity based on studies performed in hens. However, based on findings reported in a 14-day rat study, and because of the potential for occupational exposures, TBP was tested in both acute and subchronic oral neurotoxicity studies in adult rats under the auspices of a U.S. Environmental Protection Agency (EPA) final test rule on the material</abstract>
<note type="statement of responsibility">C.E. Healy, P.C. Beyrouty, B.R. Broxup</note>
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<topic>Higiene industrial</topic>
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<topic>Ensayos</topic>
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<topic>Contaminantes químicos</topic>
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<topic>Fosfato de tributilo</topic>
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<subject authority="lcshac" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080590987">
<topic>Fluidos hidráulicos</topic>
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<topic>Toxicidad</topic>
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<topic>Neurología</topic>
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<title>American Industrial Hygiene Association journal</title>
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<text>Vol. 56, nº 4, April 1995 ; p. 349-355</text>
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