Evaluation of potential toxicity from co-exposure to three CNS depressants (toluene, ethylbenzene, and xylene) under resting and working conditions using PBPK modeling

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<title>Evaluation of potential toxicity from co-exposure to three CNS depressants (toluene, ethylbenzene, and xylene) under resting and working conditions using PBPK modeling</title>
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<namePart>Dennison, James E.</namePart>
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<abstract>Under OSHA and American Conference Of Governmental Industrial Hygienists (ACGIH) guidelines, the misture formula (unity calculation) provides a method for evaluating exposures to mixtures of chemical that cause similar toxicities. According to the formula, if exposures are reduced in proportion to the number of chemical and their respective exposure limits, the overall exposure is acceptable</abstract>
<note type="statement of responsibility">James E. Dennison... [et al.]</note>
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<topic>Higiene industrial</topic>
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<topic>Contaminantes químicos</topic>
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<topic>Tolueno</topic>
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<topic>Farmacocinética</topic>
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<title>Journal of occupational and environmental hygiene</title>
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<publisher>Cincinnati, Ohio : American Industrial Hygiene Association : American Conference of Governmental Industrial Hygienists</publisher>
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<text>Vol. 2, nº 3, March 2005 ; p. 127-135</text>
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