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Hydrogen peroxide release and hydroxyl radical formation in mixtures containing mineral fibres and human neutrophils

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Registro MARC
Tag12Valor
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001  MAP20071015937
003  MAP
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008  931201e19921101gbr|||| | |00010|eng d
040  ‎$a‎MAP‎$b‎spa
084  ‎$a‎872
1001 ‎$0‎MAPA20080138455‎$a‎Leanderson, Per
24510‎$a‎Hydrogen peroxide release and hydroxyl radical formation in mixtures containing mineral fibres and human neutrophils‎$c‎Per Leanderson, Christer Tagesson
520  ‎$a‎A number of recent findings support the hypothesis that reactive oxygen metabolites play an important part in the toxic effects of asbestos and other mineral fibres. For example, asbestos has been shown to catalyse the dissociation of hidrogen peroxide (H2 O2) to hidroxyde radical (OH.), and OH. formation has also been found in aqueous buffers containing asbestos without H2 O2. In these two studies, iron was considered important for catalytic activity in generation of OH.. It was thus concluded that iron mediated damage to cells could be an important mechanism in pathogenicity of asbestos
65011‎$0‎MAPA20080585679‎$a‎Higiene industrial
65011‎$0‎MAPA20080542832‎$a‎Amianto
65011‎$0‎MAPA20080560850‎$a‎Toxicología
65011‎$0‎MAPA20080565688‎$a‎Fibra mineral
65011‎$0‎MAPA20080593780‎$a‎Sustancias químicas
65011‎$0‎MAPA20080585655‎$a‎Hidrógeno peróxido
65011‎$0‎MAPA20080580841‎$a‎Hidrógeno radical
65011‎$0‎MAPA20080538101‎$a‎Acero
65011‎$0‎MAPA20080576615‎$a‎Medicina laboral
7001 ‎$0‎MAPA20080233976‎$a‎Tagesson, Christer
7400 ‎$a‎British journal of industrial medicine
7730 ‎$t‎British journal of industrial medicine‎$d‎London and Margate‎$g‎nº 11, November 1992 ; p. 745-749