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Physiological damping of exposure variability during brief periods

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      <subfield code="a">Rappaport, Stephen M.</subfield>
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      <subfield code="a">Physiological damping of exposure variability during brief periods</subfield>
      <subfield code="c">S.M. Rappaport and R.C. Spear</subfield>
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      <subfield code="a">This paper offers a theoretical framework for considering transient exposures to chemicals which are not acuately toxic. Using a first order autoregressive model to describe short-term exposures over time in conjunction with linear toxicokinetic models of chemical disposition, distributions of body burdens are compared with those of exposure. The physiological damping of exposure variability is quantitated in terms of a transmission factor defined as the ratio of the coefficients of variation of burden and exposure</subfield>
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      <subfield code="a">Spear, Robert C.</subfield>
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      <subfield code="a">The Annals of occupational hygiene</subfield>
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      <subfield code="t">The Annals of occupational hygiene</subfield>
      <subfield code="d">Oxford [etc.]</subfield>
      <subfield code="g">nº 1, 1988 ; p. 21-33</subfield>
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