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Benchmark calculations in risk assessment using continuous dose-response information : the influence of variance and the determination of a cut-off value

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MAP20071504496
Sand, Salomon J.
Benchmark calculations in risk assessment using continuous dose-response information : the influence of variance and the determination of a cut-off value / Salomon J. Sand, Dietrich von Rosen and Agneta Falk Filipsson
In this article, a method (the hybrid approach) for benchmark calculations from continuous dose-response information is investigated. In the formulation of the methodology, a cut-off value for an adverse health effect has to be determined. It is show that the influence of variance on the hybrid model depends on the choice of determination of the cut-off point
En: Risk analysis : an international journal. - New York and London : Society for Risk Analysis. - Vol. 23, nº 5, October, 2003 ; p. 1059-1068
1. Valoración de riesgos . 2. Análisis matemático . 3. Benchmarking . 4. Análisis multivariante . I. Rosen, Dietrich von . II. Falk Filipsson, Agneta . III. PAHs . IV. Título.