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Framework for evaluation of physiologically-based pharmacokinetic models for use in safety or risk assessment

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      <subfield code="a">Framework for evaluation of physiologically-based pharmacokinetic models for use in safety or risk assessment</subfield>
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      <subfield code="a">Proposed applications of increasinggly sophisticated biologically-based computational models, such as physiologically-based pharmacokinetic models, raise the issue of how to evaluate whether the models are adequate for proposed uses, including safety or risk assessment</subfield>
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      <subfield code="t">Risk analysis : an international journal</subfield>
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      <subfield code="g">Vol. 24, nº 6, December 2004 ; p. 1697-1717</subfield>
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