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Physiologically based modeling of n-hexane kinetcis in human following inhalation exposure at rest and under physical exertion: impact on free 2,5-hexanedione in urine and on n-hexane in alveolar air

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<title>Physiologically based modeling of n-hexane kinetcis in human following inhalation exposure at rest and under physical exertion: impact on free 2,5-hexanedione in urine and on n-hexane in alveolar air</title>
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<name type="personal" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080011956">
<namePart>Hamelin, G</namePart>
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<namePart>American Industrial Hygiene Association</namePart>
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<namePart>American Conference of Governmental Industrial Hygienists</namePart>
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<dateIssued encoding="marc">2005</dateIssued>
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<abstract>This article used a modified physiologically based pharmacokinetic (PBPK) to describe-predict n-hexane (HEX) alveolar air concentrations and free 2,5-HD urinary concentrations in humans exposed to n-HEX by inhalation during a typical workweek</abstract>
<note type="statement of responsibility">G. Hamelin... [et al.]</note>
<subject authority="lcshac" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080585679">
<topic>Higiene industrial</topic>
</subject>
<subject authority="lcshac" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080605278">
<topic>Contaminantes químicos</topic>
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<subject authority="lcshac" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080548315">
<topic>N-hexano</topic>
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<subject authority="lcshac" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080536367">
<topic>BEI</topic>
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<topic>Riesgo laboral</topic>
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<topic>Control biológico</topic>
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<topic>Fisiología</topic>
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<subject authority="lcshac" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080572181">
<topic>Farmacocinética</topic>
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<topic>Inhalación</topic>
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<classification authority="">872</classification>
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<title>Journal of occupational and environmental hygiene</title>
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<publisher>Cincinnati, Ohio : American Industrial Hygiene Association : American Conference of Governmental Industrial Hygienists</publisher>
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<part>
<text>Vol. 2, nº 2, January 2005 ; p. 86-97</text>
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