Centro de Documentacion de Fundación MAPFRE - Acute and subchronic neurotoxicity studies with tri-n-butyl phosphate in adult sprague-dawley rats

MAP20071022859

Acute and subchronic neurotoxicity studies with tri-n-butyl phosphate in adult sprague-dawley rats / C.E. Healy, P.C. Beyrouty, B.R. Broxup

Sumario: Tri-n-butyl phosphate (TBP) is a liquid phosphate ester used as a component in the production of airline hydraulic fluids. The material previously had been found not to produce delayed neurotoxicity based on studies performed in hens. However, based on findings reported in a 14-day rat study, and because of the potential for occupational exposures, TBP was tested in both acute and subchronic oral neurotoxicity studies in adult rats under the auspices of a U.S. Environmental Protection Agency (EPA) final test rule on the material

En: American Industrial Hygiene Association journal. - Akron, Ohio. - Vol. 56, nº 4, April 1995 ; p. 349-355

1. Higiene industrial . 2. Ensayos . 3. Contaminantes químicos . 4. Fosfato de tributilo . 5. Fluidos hidráulicos . 6. Toxicidad . 7. Neurología . I. Beyrouty, P.C. . II. Broxup, B.R. . III. Título. IV. Título: American Industrial Hygiene Association journal.