Toxicokinetics of 2,4- and 2,6-toluenediamine in hydrolysed urine and plasma after occupational exposure to 2,4- and 2,6- toluene diisocyanate

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<title>Toxicokinetics of 2,4- and 2,6-toluenediamine in hydrolysed urine and plasma after occupational exposure to 2,4- and 2,6- toluene diisocyanate</title>
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<titleInfo type="alternative">
<title>Occupational and environmental medicine</title>
</titleInfo>
<name type="personal" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080105938">
<namePart>Lind, Pernilla</namePart>
<nameIdentifier>MAPA20080105938</nameIdentifier>
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<dateIssued encoding="marc">1996</dateIssued>
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<languageTerm type="code" authority="iso639-2b">eng</languageTerm>
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<abstract displayLabel="Summary">The objective is to assess the toxicokinetics of 2,4- and 2,6- toluene diisocyante (TDI) in chronically exposed subjects. The half life in plasma of chronically exposed workers for 2,4- and 2,6- TDA was twice as long as for volunteers with short term exposure. An indication of a two phase elimination pattern in urine was found. The first phase was related to the more recent exposure and the second, much slower one was probably realted to release of TDA in urine from TDI adducts in the body</abstract>
<note type="statement of responsibility">Pernilla Lind... [et al.]</note>
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<topic>Medicina laboral</topic>
</subject>
<subject authority="lcshac" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080619480">
<topic>Enfermedades profesionales</topic>
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<subject authority="lcshac" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080610579">
<topic>Enfermedades pulmonares</topic>
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<subject authority="lcshac" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080579708">
<topic>Control biológico</topic>
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<subject authority="lcshac" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080552824">
<topic>Toxicidad</topic>
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<subject authority="lcshac" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080605780">
<topic>Disocianato de tolueno</topic>
</subject>
<subject authority="lcshac" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080606053">
<topic>Espumas de poliuretano</topic>
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<classification authority="">873</classification>
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<title>Occupational and environmental medicine</title>
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<publisher>London and Margate</publisher>
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<part>
<text>Vol. 53, nº 2, February 1996 ; p. 94-99</text>
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