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A Simulation study of physiological factors affecting pharmacokinetic behaviour of organic solvent

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24512‎$a‎A Simulation study of physiological factors affecting pharmacokinetic behaviour of organic solvent‎$c‎A. Sato... [et al.]
520  ‎$a‎This paper discusses how physiological factors may influence the pharmacokinetic behaviour of inhaled organic solvent vapours, especially in relation to monitoring of biological exposure. To illustrate the discussion a computer based physiological pharmacokinetic model was used describing quantitatively the influence of body size, body fat content, and sex on the pharmacokienetic behaviour of trichloroethylene. Body build (body weight and body fat content), also affected the pharmacokinetic behaviour of this solvent
65011‎$0‎MAPA20080576615‎$a‎Medicina laboral
65011‎$0‎MAPA20080605278‎$a‎Contaminantes químicos
65011‎$0‎MAPA20080610579‎$a‎Enfermedades pulmonares
65011‎$0‎MAPA20080619480‎$a‎Enfermedades profesionales
65011‎$0‎MAPA20080554392‎$a‎Fisiología
65011‎$0‎MAPA20080600976‎$a‎Disolventes orgánicos
65011‎$0‎MAPA20080574215‎$a‎Tricloroetileno
65011‎$0‎MAPA20080565541‎$a‎Epidemiología
65011‎$0‎MAPA20080583163‎$a‎Vapores orgánicos
65011‎$0‎MAPA20080578824‎$a‎Análisis clínicos
7001 ‎$0‎MAPA20080016975‎$a‎Sato, Akio
7400 ‎$a‎British journal of industrial medicine
7730 ‎$t‎British journal of industrial medicine‎$d‎London and Margate‎$g‎nº 5, May 1991 ; p. 342-347