Centro de Documentacion de Fundación MAPFRE - Ethanol and food deprivation induced enhancement of hepatotoxicity in rats given carbon tetrachloride at low concentration

MAP20071016984

Ethanol and food deprivation induced enhancement of hepatotoxicity in rats given carbon tetrachloride at low concentration / H. Ikatsu, T. Okino, T. Nakajima

Sumario: It is difficult to extrapolate the dose-response relation in CCl4 (carbon tetrachloride) induced hepatotoxicity from the high concentrations used in animal studies to the low concentrations generally encountered by man in the workplace. Therefore, the dose-response relation of inhalation exposure at low concentration must be investigated when trying to determine a TLV of exposure concentration for man. In the present study, it is investigated the dose-response relations of CCl4 induced hepatic damage in chronic ethanol treated and one day food deprived rats with biochemical and histopathological methods

En: British journal of industrial medicine. - London and Margate. - nº 9, September 1991 ; p. 636-642

1. Higiene industrial . 2. Contaminantes químicos . 3. Tetracloruro de carbono . 4. Disolventes industriales . 5. Valores TLV . 6. Medicina laboral . 7. Experimentos . 8. Etanol . I. Okino, T. . II. Nakajima, Tamie . III. Título. IV. Título: British journal of industrial medicine.