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Ethanol and food deprivation induced enhancement of hepatotoxicity in rats given carbon tetrachloride at low concentration

 
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<title>Ethanol and food deprivation induced enhancement of hepatotoxicity in rats given carbon tetrachloride at low concentration</title>
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<title>British journal of industrial medicine</title>
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<namePart>Ikatsu, H.</namePart>
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<name type="personal" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080006419">
<namePart>Okino, T.</namePart>
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<name type="personal" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080142223">
<namePart>Nakajima, Tamie</namePart>
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<dateIssued encoding="marc">1991</dateIssued>
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<abstract displayLabel="Summary">It is difficult to extrapolate the dose-response relation in CCl4 (carbon tetrachloride) induced hepatotoxicity from the high concentrations used in animal studies to the low concentrations generally encountered by man in the workplace. Therefore, the dose-response relation of inhalation exposure at low concentration must be investigated when trying to determine a TLV of exposure concentration for man. In the present study, it is investigated the dose-response relations of CCl4 induced hepatic damage in chronic ethanol treated and one day food deprived rats with biochemical and histopathological methods</abstract>
<note type="statement of responsibility">H. Ikatsu, T. Okino, T. Nakajima</note>
<subject authority="lcshac" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080585679">
<topic>Higiene industrial</topic>
</subject>
<subject authority="lcshac" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080605278">
<topic>Contaminantes químicos</topic>
</subject>
<subject authority="lcshac" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080612788">
<topic>Tetracloruro de carbono</topic>
</subject>
<subject authority="lcshac" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080613839">
<topic>Disolventes industriales</topic>
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<subject authority="lcshac" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080560973">
<topic>Valores TLV</topic>
</subject>
<subject authority="lcshac" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080576615">
<topic>Medicina laboral</topic>
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<topic>Experimentos</topic>
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<subject authority="lcshac" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080540968">
<topic>Etanol</topic>
</subject>
<classification authority="">872</classification>
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<title>British journal of industrial medicine</title>
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<publisher>London and Margate</publisher>
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<part>
<text>nº 9, September 1991 ; p. 636-642</text>
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