Tissue reaction to the intrapleural injection of polyvinil chloride powder, alpha-quartz and titanium dioxide
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<title>Tissue reaction to the intrapleural injection of polyvinil chloride powder, alpha-quartz and titanium dioxide</title>
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<title>The Annals of occupational hygiene</title>
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<name type="personal" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080011666">
<namePart>Grasso, P.</namePart>
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<dateIssued encoding="marc">1983</dateIssued>
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<abstract displayLabel="Summary">A comparative study was conducted to asses the potency of three dusts -PVC, alpha-quartz and titanium dioxide- in producing fibrosis at the site of deposition when administered to rats by the intrapleural and intraperitoneal routes. PVC and TiO2 produced little reaction; this consisted mainly of macrophage accumulation with very little fibrosis which reached a peak one week after treatment and showed no evidence of further progress. On the other hand, alpha-quartz produced a severe reaction which consisted principally of fibrous tissue. The reaction was progressive and showed no sign of coming to rest by the end of the study</abstract>
<note type="statement of responsibility">P. Grasso... [et al.]</note>
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<topic>Higiene industrial</topic>
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<topic>Contaminantes químicos</topic>
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<topic>Cuarzo</topic>
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<topic>Bióxido de titanio</topic>
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<text>nº 4, 1983 ; p. 415-425</text>
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