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Evidence for an amphibole asbestos threshold exposure for asbestosis assessed by autopsy in South African asbestos miners

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MAP20071017831
Sluis-Cremer, G.K.
Evidence for an amphibole asbestos threshold exposure for asbestosis assessed by autopsy in South African asbestos miners / G.K. Sluis-Cremer, E. Hnizdo and R.S.J. Du Toit
Sumario: In an attempt to determine whether there exists a threshold asbestos dose below which asbestosis does not occur, data on 807 men who had worked on amphibole asbestos mines and undergone autopsy were analysed. When exposure was expressed as fibre-years no asbestosis was found a autopsy when exposure was up to 2 fibre-years, even after 35-45 years of residence time. In the group exposed to >2-5 fibre-years asbestosis was found. When exposure was expressed as average fibre concentration asbestosis occurred below 2 fibres per ml (f ml exp.(-1)) and the prevalence increased with residence time. In conclusion, if a threshold dose for asbestosis does exist it is at approximately 2 fibre-years if off-shift exposure is ignored
En: The Annals of occupational hygiene. - Oxford [etc.]. - nº 5, October 1990 ; p. 443-451
1. Medicina laboral . 2. Enfermedades profesionales . 3. Amianto . 4. Asbestosis . 5. Enfermedades pulmonares . 6. Epidemiología . 7. Estadísticas . 8. Minería . 9. Casos prácticos . 10. Sudáfrica . I. Hnizdo, Eva . II. Du Toit, R.S.J. . III. Título. IV. Título: The Annals of occupational hygiene.