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Physiological modelling of organic compounds

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      <subfield code="a">Andersen, Melvin E.</subfield>
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      <subfield code="c">Melvin E. Andersen</subfield>
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      <subfield code="a">Various types of mathematical model have been used to describe the pharmacokinetic behaviour of organic compounds. This present paper examines the mathematical structure and biological assumptions implicit in the use of physiological models. In addition, it discusses methods used to obtain parameters specific to particular compounds for various classes of organic compounds and the challenges involved in extending this modelling approach to an even wider variety of compounds present in occupational environments</subfield>
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      <subfield code="a">Contaminantes químicos</subfield>
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      <subfield code="a">The Annals of occupational hygiene</subfield>
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      <subfield code="t">The Annals of occupational hygiene</subfield>
      <subfield code="d">Oxford [etc.]</subfield>
      <subfield code="g">nº 3, June 1991 ; p. 309-321</subfield>
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