Centro de Documentacion de Fundación MAPFRE - Addressing nonlinearity in the exposure-response relationship for a genotoxic carcinogen : cancer potency estimates for ethylene oxide

MAP20071506259

Addressing nonlinearity in the exposure-response relationship for a genotoxic carcinogen : cancer potency estimates for ethylene oxide / C.R, Kirman... [et al.]

Introduction -- Methods -- Mode of action -- Dose-response modeling for human data sets -- Dose-response modeling for rodent data sets -- Low-dose extrapolation -- Physiologically-based pharmacokinetic modeling -- Concordance between human and rodent data sets -- Results -- Discussion-conclusions

En: Risk analysis : an international journal. - New York and London. - nº 5, October 2004 ; p. 1165-1183

1. Enfermedades pulmonares . 2. Cáncer . 3. Carcinogénesis . 4. Toxicología . 5. Oxido de etileno . 6. Laboratorios . 7. Animales . I. Kirman, C.R. . II. Título. III. Título: Risk analysis : an international journal.