Toxicological investigations on silicon carbide : in vitro cell tests and long term injection tests

<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.loc.gov/MARC21/slim http://www.loc.gov/standards/marcxml/schema/MARC21slim.xsd">
  <record>
    <leader>00000nab a2200000 i 4500</leader>
    <controlfield tag="001">MAP20071015722</controlfield>
    <controlfield tag="003">MAP</controlfield>
    <controlfield tag="005">20080418114328.0</controlfield>
    <controlfield tag="007">hzruuu---uuuu</controlfield>
    <controlfield tag="008">931123e19930901gbr||||    | |00010|eng d</controlfield>
    <datafield tag="040" ind1=" " ind2=" ">
      <subfield code="a">MAP</subfield>
      <subfield code="b">spa</subfield>
    </datafield>
    <datafield tag="084" ind1=" " ind2=" ">
      <subfield code="a">873</subfield>
    </datafield>
    <datafield tag="245" ind1="1" ind2="0">
      <subfield code="a">Toxicological investigations on silicon carbide</subfield>
      <subfield code="b">: in vitro cell tests and long term injection tests</subfield>
      <subfield code="c">J. Bruch... [et al.]</subfield>
    </datafield>
    <datafield tag="520" ind1=" " ind2=" ">
      <subfield code="a">Silicon carbide (SiC) dust and other dusts for comparison were injected intratracheally at a high dose into rats and the response of the lungs and the lymph nodes was studied after an appropriate experimental period. The indices studied were: histological changes in the lung and lymph nodes, organ weights, the formation of collagenous fibres, and the appearance of quartz typical areas. According to several epidemiological animal studies, SiC changes in the tissues studied in terms of damaging fibrogenic effects could be found after eight months and three and 12 months</subfield>
    </datafield>
    <datafield tag="650" ind1="1" ind2="1">
      <subfield code="0">MAPA20080576615</subfield>
      <subfield code="a">Medicina laboral</subfield>
    </datafield>
    <datafield tag="650" ind1="1" ind2="1">
      <subfield code="0">MAPA20080619480</subfield>
      <subfield code="a">Enfermedades profesionales</subfield>
    </datafield>
    <datafield tag="650" ind1="1" ind2="1">
      <subfield code="0">MAPA20080560850</subfield>
      <subfield code="a">Toxicología</subfield>
    </datafield>
    <datafield tag="650" ind1="1" ind2="1">
      <subfield code="0">MAPA20080583934</subfield>
      <subfield code="a">Carburo de silicio</subfield>
    </datafield>
    <datafield tag="650" ind1="1" ind2="1">
      <subfield code="0">MAPA20080610579</subfield>
      <subfield code="a">Enfermedades pulmonares</subfield>
    </datafield>
    <datafield tag="650" ind1="1" ind2="1">
      <subfield code="0">MAPA20080585679</subfield>
      <subfield code="a">Higiene industrial</subfield>
    </datafield>
    <datafield tag="650" ind1="1" ind2="1">
      <subfield code="0">MAPA20080539948</subfield>
      <subfield code="a">Tests</subfield>
    </datafield>
    <datafield tag="650" ind1="1" ind2="1">
      <subfield code="0">MAPA20080614539</subfield>
      <subfield code="a">Investigación científica</subfield>
    </datafield>
    <datafield tag="650" ind1="1" ind2="1">
      <subfield code="0">MAPA20080565541</subfield>
      <subfield code="a">Epidemiología</subfield>
    </datafield>
    <datafield tag="700" ind1="1" ind2=" ">
      <subfield code="0">MAPA20080003586</subfield>
      <subfield code="a">Bruch, J.</subfield>
    </datafield>
    <datafield tag="740" ind1="0" ind2=" ">
      <subfield code="a">British journal of industrial medicine</subfield>
    </datafield>
    <datafield tag="773" ind1="0" ind2=" ">
      <subfield code="t">British journal of industrial medicine</subfield>
      <subfield code="d">London and Margate</subfield>
      <subfield code="g">nº 9, September 1993 ; p. 807-813</subfield>
    </datafield>
  </record>
</collection>