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Notes: Sumario: Published data suggest that particle charge could be related to its toxicity. Respirable particles containing silica were therefore collected in foundries and their charge measured. These particles carried high levels of positive charge that were related to low humidity. incubating these particles with pulmonary macrophages from mice produced detectable activities of collagenase, aprecursor of silicosis. These experiments confirm that the toxicity of silica particles is likely to be because of the positive charge they carryRelated records: En: British journal of industrial medicine. - London and Margate. - nº 3, March 1992 ; p. 163-166Materia / lugar / evento: Medicina laboral Enfermedades profesionales Silicosis Sílice Polvo de sílice Experimentos Toxicidad Secondary titles: Título: British journal of industrial medicine
Other categories: 873

What makes silica toxic?