Effect of silica on the rat lung with special reference to RNA

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      <subfield code="a">Effect of silica on the rat lung with special reference to RNA</subfield>
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      <subfield code="a">The chemical progress of silicosis in rat lungs was studied after a single intratracheal injection of 50 mg SiO2. It is concluded that the metabolism of RNA changed in experimental silicosis; mRNA increased very markedly and collagen accumulated more than total nitrogen or wet weight. A pronounced increase was observed in cholesterol and phospholipids, the peak of phospholipids preceding that of cholesterol</subfield>
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