Centro de Documentacion de Fundación MAPFRE - Quantification on biological variability

MAP20071018017

Quantification on biological variability / P.O. Droz

Sumario: Pharmacokinetic models are usually developed to describe the kinetic behaviour of the chemical compounds in an average human body. There are however many situations were the effects of variations in a given pharmacokinetic parameter would be of interest. For example, in biological monitoring, the variability of biological data is a critical parameter when relating air and biological measures of an individual exposure. This paper reviews two possible approaches for the simulation of such variability in occupational pharmacokinetics

En: The Annals of occupational hygiene. - Oxford [etc.]. - nº 3, June 1992 ; p. 295-306

1. Higiene industrial . 2. Contaminantes químicos . 3. Productos químicos . 4. Medicamentos . 5. Biología . 6. Muestreos . 7. Medicina laboral . I. Title. II. Título: The Annals of occupational hygiene.