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Addressing nonlinearity in the exposure-response relationship for a genotoxic carcinogen : cancer potency estimates for ethylene oxide

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<title>Addressing nonlinearity in the exposure-response relationship for a genotoxic carcinogen</title>
<subTitle>: cancer potency estimates for ethylene oxide</subTitle>
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<title>Risk analysis : an international journal</title>
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<name type="personal" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080047733">
<namePart>Kirman, C.R.</namePart>
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<placeTerm type="code" authority="marccountry">usa</placeTerm>
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<dateIssued encoding="marc">2004</dateIssued>
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<abstract>Introduction -- Methods -- Mode of action -- Dose-response modeling for human data sets -- Dose-response modeling for rodent data sets -- Low-dose extrapolation -- Physiologically-based pharmacokinetic modeling -- Concordance between human and rodent data sets -- Results --  Discussion-conclusions</abstract>
<note type="statement of responsibility">C.R, Kirman... [et al.]</note>
<subject authority="lcshac" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080610579">
<topic>Enfermedades pulmonares</topic>
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<subject authority="lcshac" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080540500">
<topic>Cáncer</topic>
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<subject authority="lcshac" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080568269">
<topic>Carcinogénesis</topic>
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<topic>Toxicología</topic>
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<subject authority="lcshac" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080576974">
<topic>Oxido de etileno</topic>
</subject>
<subject authority="lcshac" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080563134">
<topic>Laboratorios</topic>
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<topic>Animales</topic>
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<title>Risk analysis : an international journal</title>
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<publisher>New York and London</publisher>
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<text>nº 5, October 2004 ; p. 1165-1183</text>
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