Pesquisa de referências

Can discourse processing performance serve as an early marker of Alzheimer's disease and mild cognitive impairment? A systematic review of text comprehension

Can discourse processing performance serve as an early marker of Alzheimer's disease and mild cognitive impairment? A systematic review of text comprehension
Recurso electrónico / Electronic resource
Seção: Artigos
Título: Can discourse processing performance serve as an early marker of Alzheimer's disease and mild cognitive impairment? A systematic review of text comprehension / Eesha Kokje...[et.al]
Notas: Sumario: A number of linguistic and cognitive deficits have been reported during the course of Alzheimer's disease (AD) and its preceding stage of mild cognitive impairment (MCI), with some deficits appearing years before onset of clinical symptoms. It continues to be a critical task to identify tools that may serve as an early marker of pathology that are also reliably able to distinguish AD from normal ageing. Given the limited success of classic psychometric cognitive testing, a novel approach in assessment is warranted. A potentially sensitive assessment paradigm is discourse processing. The aim of this review was to synthesize original research studies investigating comprehension of discourse in AD and MCI, and to evaluate the potential of this paradigm as a promising avenue for further research. A literature search targeting studies with AD or MCI groups over 60 years of age was conducted in PubMed, Web of Science, and PsycINFO databases. Eight articles with good quality were included in the review. Six measures of discourse comprehensionnaming latency, summary, lesson, main idea, proportion of inferential clauses, true/false questionswere identified. All eight studies reported significant deficits in discourse comprehension in AD and MCI groups on five of the six measures, when compared to cognitively healthy older adults. Mixed results were observed for associations with commonly used cognitive measures. Given the consistent findings for discourse comprehension measures across all studies, we strongly recommend further research on its early predictive potential, and discuss different avenues for research.

Registros relacionados: En: European Journal of Ageing : social, behavioural and health perspectives. - Cham, Switzerland [etc.] : Springer International Publishing AG, 2021-. - 07/03/2022 Volumen 19 Número 1 - 2022 , p. 3-18Materia / lugar / evento: Alzheimer Deterioro cognitivo Esperanza de vida Ageingnomics. Economia senior Otros autores: Kokje, Eesha
Outras classificações: 931.2
Direitos: La copia digital se distribuye bajo licencia "Attribution 4.0 International (CC BY 4.0)"
Ver detalhe do número