Centro de Documentacion de Fundación MAPFRE - Dynamics of pulmonary surfactant system and its role in alveolar cleansing

MAP20071017814

Dynamics of pulmonary surfactant system and its role in alveolar cleansing / Albert Podgorski and Leon Gradon

Sumario: Qualitative descriptions of the surfactant film behaviour and the concept of hydrodynamical clearance in the alveoli are presented, and the possibilities of modelling of dynamics of the system mathematically are discussed. Using the model formulated it is shown that under dynamic conditions physicochemical surface phenomena may lead to net flow of the liquid layer (together with the dust particles) out of the alveoli. The effects of some parameters ( surfactant activity and its production, viscosity of the liquid layer, size and geometry of the bronchoalveolar system, shape of respiratory curve) on the clearance rate are demonstrated. The resuts obtained are discussed critically

En: The Annals of occupational hygiene. - Oxford [etc.]. - nº 2, April 1990 ; p. 137-147

1. Medicina . 2. Vías respiratorias . 3. Inhalación . 4. Limpieza . 5. Ecuaciones matemáticas . I. Gradon, Leon . II. Título. III. Título: The Annals of occupational hygiene.