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Toxicokinetics of 2,4- and 2,6-toluenediamine in hydrolysed urine and plasma after occupational exposure to 2,4- and 2,6- toluene diisocyanate
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MAP20071025534
Toxicokinetics of 2,4- and 2,6-toluenediamine in hydrolysed urine and plasma after occupational exposure to 2,4- and 2,6- toluene diisocyanate / Pernilla Lind... [et al.]
Sumario: The objective is to assess the toxicokinetics of 2,4- and 2,6- toluene diisocyante (TDI) in chronically exposed subjects. The half life in plasma of chronically exposed workers for 2,4- and 2,6- TDA was twice as long as for volunteers with short term exposure. An indication of a two phase elimination pattern in urine was found. The first phase was related to the more recent exposure and the second, much slower one was probably realted to release of TDA in urine from TDI adducts in the body
En: Occupational and environmental medicine. - London and Margate. - Vol. 53, nº 2, February 1996 ; p. 94-99
1. Medicina laboral ‌. 2. Enfermedades profesionales ‌. 3. Enfermedades pulmonares ‌. 4. Control biológico ‌. 5. Toxicidad ‌. 6. Disocianato de tolueno ‌. 7. Espumas de poliuretano ‌. I. Lind, Pernilla ‌. II. Título. III. Título: Occupational and environmental medicine.