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Effects of ethanol and phenobarbital treatments on the pharmacokinetics of tolueno in rats

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008  940127e19920201gbr|||| | |00010|eng d
035  ‎$a‎6800002951
040  ‎$a‎MAP‎$b‎spa
084  ‎$a‎873
1001 ‎$0‎MAPA20080151522‎$a‎Wang, Rui-Sheng
24510‎$a‎Effects of ethanol and phenobarbital treatments on the pharmacokinetics of tolueno in rats‎$c‎Rui-Sheng Wang, Tamie Nakajima
520  ‎$a‎In this present study, it investigated the in vivo metabolic pattern of tolueno in rats, especially the pattern of urinary excretion of toluene metabolites, at seven exposure concentrations ranging betwen 50 and 4000 ppm. The effect of ethanol and phenobarbital treatments on toluene pharmacokinetics was also studied in that these two chemical induce different types of cytochrome P-450 that are known to be insolved in toluene metabolisme in vitro
65011‎$0‎MAPA20080576615‎$a‎Medicina laboral
65011‎$0‎MAPA20080562410‎$a‎Experimentos
65011‎$0‎MAPA20080608286‎$a‎Reacciones metabólicas
65011‎$0‎MAPA20080605278‎$a‎Contaminantes químicos
65011‎$0‎MAPA20080545574‎$a‎Tolueno
65011‎$0‎MAPA20080540968‎$a‎Etanol
7001 ‎$0‎MAPA20080142223‎$a‎Nakajima, Tamie
7400 ‎$a‎British journal of industrial medicine
7730 ‎$t‎British journal of industrial medicine‎$d‎London and Margate‎$g‎nº 2, February 1992 ; p. 104-112