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Solubility of rockwool fibres in vivo and the formation of pseudo-asbestos bodies

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Tag12Value
LDR  00000nab a2200000 i 4500
001  MAP20071017536
003  MAP
005  20080418115105.0
007  hzruuu---uuuu
008  940221s1984 gbr|||| | |00010|eng d
035  ‎$a‎6800003336
040  ‎$a‎MAP‎$b‎spa
084  ‎$a‎872
1001 ‎$0‎MAPA20080015039‎$a‎Morgan, A.
24510‎$a‎Solubility of rockwool fibres in vivo and the formation of pseudo-asbestos bodies‎$c‎A. Morgan, A. Holmes
520  ‎$a‎sized rockwool fibres were administred to rats by intratracheal instillation to study their solubility in the lung, and also to hamsters to study the formation of pseudo-asbestos bodies. Rats were killed serially and the fibres recovered by digesting lungs with hypochlorite solution. Count median diameters (CMDs) of the recovered fibres were measured at their centres with the ligth microscope and, after 18 months, there was no significant change in CMD. Even after six months, however, it was apparent that fibres were becoming thinner at their ends than in the middle so that slow dissolution does occur. The formation of pseudo-asbestos bodies on rockwood fibres in the hamster lung followed a similar time course to that for anthophyllite asbestos and glass fibres
65011‎$0‎MAPA20080585679‎$a‎Higiene industrial
65011‎$0‎MAPA20080605278‎$a‎Contaminantes químicos
65011‎$0‎MAPA20080563141‎$a‎Lana mineral
65011‎$0‎MAPA20080624408‎$a‎Fibras minerales artificiales
65011‎$0‎MAPA20080588939‎$a‎Aislamiento térmico
65011‎$0‎MAPA20080562410‎$a‎Experimentos
65011‎$0‎MAPA20080588670‎$a‎Vías respiratorias
7001 ‎$0‎MAPA20080012380‎$a‎Holmes, A.
7404 ‎$a‎The Annals of occupational hygiene
7730 ‎$t‎The Annals of occupational hygiene‎$d‎Oxford [etc.]‎$g‎nº 3, 1984 ; p. 307-314