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Accumulation of inhaled mineral dust in the lung and associated lymph nodes : implications for exposure and dose in occupational lung disease

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008  940207s1987 gbr|||| | |00010|eng d
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24510‎$a‎Accumulation of inhaled mineral dust in the lung and associated lymph nodes‎$b‎: implications for exposure and dose in occupational lung disease‎$c‎J.H. Vincent... [et al.]
520  ‎$a‎Experiments have been carried out using laboratory rats exposed to non-fibrous, toxic and non-toxic, and relatively insoluble mineral fusts under chronic exposure conditions for airborne respirable concentrations from 0.1 to 90 mg m-3. The aim was to investigate the accumulation of dust in the lung and associated lymph nodes. The results have shown consistently that, after initial non-linear phase during the early part of the exposure history, lung burden becomes a linearly-increasing function of exposure time. Furthermore, lung burden increases directly with respect to the respirable concentration over the full range of conditions examined
65011‎$0‎MAPA20080576615‎$a‎Medicina laboral
65011‎$0‎MAPA20080619480‎$a‎Enfermedades profesionales
65011‎$0‎MAPA20080610579‎$a‎Enfermedades pulmonares
65011‎$0‎MAPA20080585679‎$a‎Higiene industrial
65011‎$0‎MAPA20080542832‎$a‎Amianto
65011‎$0‎MAPA20080539566‎$a‎Polvo
65011‎$0‎MAPA20080570484‎$a‎Riesgo laboral
65011‎$0‎MAPA20080562410‎$a‎Experimentos
7001 ‎$0‎MAPA20080209582‎$a‎Vincent, James H.
7404 ‎$a‎The Annals of occupational hygiene
7730 ‎$t‎The Annals of occupational hygiene‎$d‎Oxford [etc.]‎$g‎nº 3, 1987 ; p. 375-393