Centro de Documentacion de Fundación MAPFRE - Effect of silica on the rat lung with special reference to RNA

MAP20071017423

Effect of silica on the rat lung with special reference to RNA / P. Lehtinen, S. Aho and E. Kulonen

Sumario: The chemical progress of silicosis in rat lungs was studied after a single intratracheal injection of 50 mg SiO2. It is concluded that the metabolism of RNA changed in experimental silicosis; mRNA increased very markedly and collagen accumulated more than total nitrogen or wet weight. A pronounced increase was observed in cholesterol and phospholipids, the peak of phospholipids preceding that of cholesterol

En: The Annals of occupational hygiene. - Oxford [etc.]. - nº 1, 1983 ; p. 81-87

1. Higiene industrial . 2. Contaminantes químicos . 3. Sílice . 4. Enfermedades profesionales . 5. Enfermedades pulmonares . 6. Silicosis . 7. Medicina laboral . 8. RNA . 9. Experimentos . I. Aho, S. . II. Kulonen, P. . III. Título. IV. Título: The Annals of occupational hygiene.