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MAP20071017423Lehtinen, P.Effect of silica on the rat lung with special reference to RNA / P. Lehtinen, S. Aho and E. KulonenSumario: The chemical progress of silicosis in rat lungs was studied after a single intratracheal injection of 50 mg SiO2. It is concluded that the metabolism of RNA changed in experimental silicosis; mRNA increased very markedly and collagen accumulated more than total nitrogen or wet weight. A pronounced increase was observed in cholesterol and phospholipids, the peak of phospholipids preceding that of cholesterolEn: The Annals of occupational hygiene. - Oxford [etc.]. - nº 1, 1983 ; p. 81-871. Higiene industrial. 2. Contaminantes químicos. 3. Sílice. 4. Enfermedades profesionales. 5. Enfermedades pulmonares. 6. Silicosis. 7. Medicina laboral. 8. RNA. 9. Experimentos. I. Aho, S.. II. Kulonen, P.. III. Título. IV. Título: The Annals of occupational hygiene.