Evidence for an amphibole asbestos threshold exposure for asbestosis assessed by autopsy in South African asbestos miners

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<title>Evidence for an amphibole asbestos threshold exposure for asbestosis assessed by autopsy in South African asbestos miners</title>
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<title>The Annals of occupational hygiene</title>
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<name type="personal" usage="primary" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080233259">
<namePart>Sluis-Cremer, G.K.</namePart>
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<name type="personal" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080026196">
<namePart>Hnizdo, Eva</namePart>
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<name type="personal" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080129361">
<namePart>Du Toit, R.S.J.</namePart>
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<dateIssued encoding="marc">1990</dateIssued>
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<abstract displayLabel="Summary">In an attempt to determine whether there exists a threshold asbestos dose below which asbestosis does not occur, data on 807 men who had worked on amphibole asbestos mines and undergone autopsy were analysed. When exposure was expressed as fibre-years no asbestosis was found a autopsy when exposure was up to 2 fibre-years, even after 35-45 years of residence time. In the group exposed to >2-5 fibre-years asbestosis was found. When exposure was expressed as average fibre concentration asbestosis occurred below 2 fibres per ml (f ml exp.(-1)) and the prevalence increased with residence time. In conclusion, if a threshold dose for asbestosis does exist it is at approximately 2 fibre-years if off-shift exposure is ignored</abstract>
<note type="statement of responsibility">G.K. Sluis-Cremer, E. Hnizdo and R.S.J. Du Toit</note>
<subject authority="lcshac" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080576615">
<topic>Medicina laboral</topic>
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<subject authority="lcshac" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080619480">
<topic>Enfermedades profesionales</topic>
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<topic>Amianto</topic>
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<topic>Asbestosis</topic>
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<topic>Enfermedades pulmonares</topic>
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<topic>Epidemiología</topic>
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<topic>Estadísticas</topic>
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<topic>Minería</topic>
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<topic>Casos prácticos</topic>
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<topic>Sudáfrica</topic>
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<publisher>Oxford [etc.]</publisher>
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<text>nº 5, October 1990 ; p. 443-451</text>
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