Asbestos induced oxidative injury to DNA

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<rdf:Description>
<dc:creator>Mahmood, N.</dc:creator>
<dc:date>1993-06-01</dc:date>
<dc:description xml:lang="es">Sumario: DNA-damaging effects of asbestos in the presence of organic peroxides and hydroperoxides were investigated. The destabilization of the secondary structure of DNA, damage to deoxyribose sugar and DNA fidelity were measured, respectively, by S-1 nuclease hydrolysis, the formation of thiobarbituric acid (TBA)-reacting species and a melting temperature (Tm) profile using calf thymus DNA. These results suggest that asbestos in the presence of organic peroxides and hydroperoxides damage the DNA which is mediated by the generation of oxygen free radicals</dc:description>
<dc:identifier>https://documentacion.fundacionmapfre.org/documentacion/publico/es/bib/48161.do</dc:identifier>
<dc:language>eng</dc:language>
<dc:rights xml:lang="es">InC - http://rightsstatements.org/vocab/InC/1.0/</dc:rights>
<dc:subject xml:lang="es">Higiene industrial</dc:subject>
<dc:subject xml:lang="es">Contaminantes químicos</dc:subject>
<dc:subject xml:lang="es">Amianto</dc:subject>
<dc:subject xml:lang="es">Contaminación atmosférica</dc:subject>
<dc:subject xml:lang="es">Oxidación</dc:subject>
<dc:subject xml:lang="es">Enfermedades profesionales</dc:subject>
<dc:subject xml:lang="es">ADN</dc:subject>
<dc:subject xml:lang="es">Riesgo laboral</dc:subject>
<dc:type xml:lang="es">Artículos y capítulos</dc:type>
<dc:title xml:lang="es">Asbestos induced oxidative injury to DNA</dc:title>
<dc:title xml:lang="es">Título: The Annals of occupational hygiene</dc:title>
<dc:relation xml:lang="es">En: The Annals of occupational hygiene. - Oxford [etc.]. - nº 3, June 1993 ; p. 315-319</dc:relation>
</rdf:Description>
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