Benchmark calculations in risk assessment using continuous dose-response information : the influence of variance and the determination of a cut-off value

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<title>Benchmark calculations in risk assessment using continuous dose-response information</title>
<subTitle>: the influence of variance and the determination of a cut-off value</subTitle>
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<name type="personal" usage="primary" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080178048">
<namePart>Sand, Salomon J.</namePart>
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<namePart>Rosen, Dietrich von</namePart>
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<name type="personal" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080300166">
<namePart>Falk Filipsson, Agneta</namePart>
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<dateIssued encoding="marc">2003</dateIssued>
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<abstract>In this article, a method (the hybrid approach) for benchmark calculations from continuous dose-response information is investigated. In the formulation of the methodology, a cut-off value for an adverse health effect has to be determined. It is show that the influence of variance on the hybrid model depends on the choice of determination of the cut-off point</abstract>
<note type="statement of responsibility">Salomon J. Sand, Dietrich von Rosen and Agneta Falk Filipsson</note>
<subject authority="lcshac" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080604394">
<topic>Valoración de riesgos</topic>
</subject>
<subject authority="lcshac" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080589004">
<topic>Análisis matemático</topic>
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<subject authority="lcshac" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080561499">
<topic>Benchmarking</topic>
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<subject authority="lcshac" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="MAPA20080604721">
<topic>Análisis multivariante</topic>
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<classification authority="">937.41</classification>
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<title>Risk analysis : an international journal</title>
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<publisher>New York and London : Society for Risk Analysis</publisher>
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<part>
<text>Vol. 23, nº 5, October, 2003 ; p. 1059-1068</text>
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