Centro de Documentación de Fundación MAPFRE - The Impact of cytochrome P450 2E1-dependent metabolic variance on a risk-relevant pharmacokinetic outcome

Notas: Risk assessment include assumptions about sensitive subpopulations, such as the fraction of the general population that is sensitive and the extent that biochemical or physiological attributes influence sensitivity. Uncertainty factor account for both pharmacokinetic (PK) and pharmacodynamic (PD) components, allowing the inclusin of risk-relevant information to replace default assumptions about PK and PD variance (uncertainty)Registros relacionados: En: Risk analysis : an international journal. - New York and London : Society for Risk Analysis. - Vol. 23, nº 6, December, 2003 ; p. 1221-1238Materia / lugar / evento: Citrocromo P-450 TCP Medicina laboral Epidemiología Plantas químicas Riesgo laboral Otros autores: Lipscomb, John C.
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