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MAP20071017873Andersen, Melvin E.Physiological modelling of organic compounds / Melvin E. AndersenSumario: Various types of mathematical model have been used to describe the pharmacokinetic behaviour of organic compounds. This present paper examines the mathematical structure and biological assumptions implicit in the use of physiological models. In addition, it discusses methods used to obtain parameters specific to particular compounds for various classes of organic compounds and the challenges involved in extending this modelling approach to an even wider variety of compounds present in occupational environmentsEn: The Annals of occupational hygiene. - Oxford [etc.]. - nº 3, June 1991 ; p. 309-3211. Higiene industrial. 2. Contaminantes químicos. 3. Metabolitos. 4. Fisiología. I. Título. II. Título: The Annals of occupational hygiene.