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A Review of exposure conditions and possible health effects associated with aerosol and vapour from low-aromatic oil-based drilling fluids

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1001 ‎$0‎MAPA20080001384‎$a‎Eide, I.
24512‎$a‎A Review of exposure conditions and possible health effects associated with aerosol and vapour from low-aromatic oil-based drilling fluids‎$c‎I. Eide
520  ‎$a‎This paper reviews investigations on possible heath effects after inhalation of aerosol and vapour from the low-aromatic oil-based drilling fluids which have replaced the diesel-based fluids. The main advantage of the low-aromatic base oils with respect to health hazard is their lower volatility. However, some aliphatic and naphthenic hydrocarbons are distributed more efficiently to the brain than are the corresponding aromatic ones. Reducing the content of aromatic hydrocarbons becomes particularly important when the upper end of the boiling point range is sufficiently high for the base oil to contain carcinogenic polycyclic aromatic hydrocarbons (PAH). As a result of enclosure and local extract ventilation it has been possible to reduce time-weighted average concentrations of aerosol and vapour to below 100 mg m exp.(-3). Effects on the central nervous system have only been observed at higher concentrations of the actual hydrocarbons, and male rat hydrocarbon nephropathy is not considered predictive of a normal human response. Insufficient information is available on possible long-term effects of exposure to the low-aromatic oil-based drilling fluids, especially regarding carcinogenicity and changes in the lungs
65011‎$0‎MAPA20080585679‎$a‎Higiene industrial
65011‎$0‎MAPA20080605278‎$a‎Contaminantes químicos
65011‎$0‎MAPA20080549534‎$a‎Aerosoles
65011‎$0‎MAPA20080576615‎$a‎Medicina laboral
65011‎$0‎MAPA20080630195‎$a‎Hidrocarburo aromático policíclico
65011‎$0‎MAPA20080545673‎$a‎Vapores
65011‎$0‎MAPA20080619480‎$a‎Enfermedades profesionales
65011‎$0‎MAPA20080588670‎$a‎Vías respiratorias
65011‎$0‎MAPA20080615437‎$a‎Sistema Nervioso Central
65011‎$0‎MAPA20080610579‎$a‎Enfermedades pulmonares
65011‎$0‎MAPA20080540500‎$a‎Cáncer
65011‎$0‎MAPA20080560850‎$a‎Toxicología
65011‎$0‎MAPA20080562410‎$a‎Experimentos
7404 ‎$a‎The Annals of occupational hygiene
7730 ‎$t‎The Annals of occupational hygiene‎$d‎Oxford [etc.]‎$g‎nº 2, April 1990 ; p. 149-157